Transcription:
The Nerve Growth Factor in Alzheimer’s Disease Study
Alzheimer’s Disease affects millions of people worldwide, the main symptoms are caused by the degeneration of brain cells that control memory and thinking. These cells are originated in the nucleus pulposus and communicate with the hippocampus and cerebral cortex. As these cells to degenerate they lose their ability to produce acidic alkaline and communicate with other cells, current medicines improve Alzheimer’s symptoms for several years, but become ineffective as the disease progresses.
An experiment with bio pharmaceutical drug called CERE-110 has been tested in over 35 people with Alzheimer’s disease.
CERE-110 is intended to restore damaged cholinergic cells and protect them from further degeneration.
CERE-110 consists of viral vector that contains only the gene for human nerve growth factor and NGF and naturally occurring neurotrophic factor. This viral vector serves as carrier for delivering NGF to brain cells. Neurosurgeons accurately deliver CERE-110 to the area of the brain. where neurons are to degenerating.
CERE-110 then address the neuron inducing them to produce a continuous lifelong supply of NGF.
NGF is expected to restore the function of neurons and protect them from further the de generation. Hence potentially reducing the severity symptoms, slowly disease progression. A new study is now in the way to test the potential benefits and safety of CERE-110 in Alzheimer’s disease.
For more information, please visit http://www.adcs.org select the NGF study link.
DISCLAIMER: The views and statements expressed in this video are those of the Alzheimer’s Disease Cooperative Study(ADCS) and Ceregene, Inc. and intended to provide an artistic interpretation of the experimental product.In no event should the statements included be considered a representation or warranty by ADCS or Ceregene as to the safety and/or efficacy of the product.This video is not intended to Viewers should consult their physician or contact one of the participating centres for more information about CERE-110. THis product has not been approved by the FDA and the statements in this video have not been endorsed by the FDA.
